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Jan 31, 2026 Your immune system is supposed to protect you

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Notably, these morphological changes are not unique to cuproptosis and may overlap with or be similar to those of other types of cell death

identify an unexpected metabolic underlying mechanism for this disease: the lipid chaperone fatty-acid-binding protein 5 (FABP5) aggravates psoriatic inflammation by driving keratinocytes into ferroptosis, a form of regulated cell death induced by iron-dependent lipid peroxidation (Fig